l General Information |
Product Name | Dinaciclib |
General description | Dinaciclib is a pyrazolo[1,5-a]pyrimidine with potential antineoplastic activity. It selectively inhibits cyclin dependent kinases CDK1, CDK2, CDK5, and CDK9. |
Synonym | 2-[(2S)-1-[3-ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol; SCH727965 |
Purity | ≥98.0%(HPLC) | CAS Number | 779353-01-4 |
Formula | C21H28N6O2 | Molecular Weight | 396.49 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Solid |
Solubility(25℃) | DMSO | ≥20mg/mL |
Ethanol | ≥5mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Dinaciclib is a pyrazolo[1,5-a]pyrimidine with potential antineoplastic activity. Dinaciclib selectively inhibits cyclin dependent kinases CDK1, CDK2, CDK5, and CDK9; inhibition of CDK1 and CDK2 may result in cell cycle repression and tumor cell apoptosis. |
l Packaging & Storage |
Packaging | 5mg; 25mg; 100mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
