l General Information |
Product Name | Norfloxacin |
General description | Norfloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria |
Synonym | 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid; MK-0366 |
Purity | ≥99.0%(HPLC) | CAS Number | 70458-96-7 |
Formula | C16H18FN3O3 | Molecular Weight | 319.336 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or pale yellow solid |
Solubility(25℃) | DMSO | Slightly soluble |
Ethanol | Slightly soluble |
Water | Very slightly soluble |
l Biological Information |
Biochem/Physiol Actions | Norfloxacin is a synthetic, broad-spectrum fluoroquinolone with antibacterial activity. Norfloxacin inhibits activity of DNA gyrase, thereby blocking bacterial DNA replication. Norfloxacin concentrates in the renal tubules and bladder and is bactericidal against a wide range of aerobic gram-positive and gram-negative organisms. |
Application | 1. Topoisomerase II Inhibitors Compounds that inhibit the activity of DNA Topoisomerase II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. 2. Cytochrome P-450 CYP1A2 Inhibitors Drugs and compounds which inhibit or antagonize the biosynthesis or actions of Cytochrome P-450 CYP1A2 3. Anti-Bacterial Agents Substances that inhibit the growth or reproduction of Bacteria. |
l Packaging & Storage |
Packaging | 250mg; 1g; 5g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
