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Curcumin

Product #: TL0456
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Details

l  General Information

Product Name

Curcumin

General description

Curcumin is a natural component of the rhizome of turmeric. Its biological effects range from antioxidant, anti-inflammatory to inhibition of angiogenesis and is also shown to possess specific antitumoral activity.

Synonym

Diferuloylmethane; Diferulylmethane; Natural Yellow 3

Purity

≥98%(HPLC)

CAS Number

458-37-7

Formula

C21H20O6

Molecular Weight

368.38

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Yellow solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

Curcumin is a phytopolylphenol pigment isolated from the plant Curcuma longa, commonly known as turmeric, with a variety of pharmacologic properties. Curcumin blocks the formation of reactive oxygen species, possesses anti-inflammatory properties as a result of inhibition of cyclooxygenases (COX) and other enzymes involved in inflammation; and disrupts cell signal transduction by various mechanisms including inhibition of protein kinase C. These effects may play a role in the agent's observed antineoplastic properties, which include inhibition of tumor cell proliferation and suppression of chemically induced carcinogenesis and tumor growth in animal models of cancer.

Application

1. Anti-Inflammatory Agents, Non-Steroidal

2. Enzyme Inhibitors

3. Antineoplastic Agents

4. Coloring Agents

l  Packaging & Storage

Packaging

50mg; 1g

Storage temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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