l General Information |
Product Name | Ampicillin |
General description | Ampicillin Trihydrate is a broad-spectrum semisynthetic derivative of aminopenicillin. |
Synonym | D-(−)-α-Aminobenzylpenicillin; NCI-C56086 |
Purity | ≥98%(HPLC) | CAS Number | 69-53-4 |
Formula | C16H19N3O4S | Molecular Weight | 349.40 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or almost white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | ~2mg/mL |
l Biological Information |
Biochem/Physiol Actions | Ampicillin is a broad-spectrum, semi-synthetic, beta-lactam penicillin antibiotic with bactericidal activity. Ampicillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-age of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis. Ampicillin is stable against hydrolysis by a variety of beta-lactamases, therefore, can be used in wide range of gram-positive and -negative infections. |
Application | Anti-Bacterial Agents |
l Packaging & Storage |
Packaging | 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
