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Droxidopa

Product #: TL0420
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Details

l  General Information

Product Name

Droxidopa

General description

Droxidopa is a precursor of noradrenaline that is used in the treatment of parkinsonism.

Synonym

L-threo 3,4-Dihydroxyphenylserine; L-DOPS

Purity

≥98%(HPLC)

CAS Number

23651-95-8

Formula

C9H11NO5

Molecular Weight

213.19

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Yellow white solid

Solubility(25℃)

DMSO

Insoluble

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

Droxidopa is an orally active synthetic precursor of norepinephrine that increases the deficient supply of norepinephrine in patients with NOH, thereby improving orthostatic blood pressure and alleviating associated symptoms of lightheadedness, dizziness, blurred vision, and syncope through the induction of tachycardia (increased heart rate) and hypertension.

Application

Antiparkinson Agents

l  Packaging & Storage

Packaging

250mg; 1g

Storage temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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