l General Information |
Product Name | Triamcinolon Acetonide |
General description | Triamcinolone acetonide is a synthetic glucocorticoid, used in the symptomatic treatment of inflammation. |
Synonym | 9α-Fluoro-11β,16α,17α,21-tetrahydroxy-1,4-pregnadiene-3,20-dione 16,17-acetonide |
Purity | ≥98%(HPLC) | CAS Number | 76-25-5 |
Formula | C24H31FO6 | Molecular Weight | 434.50 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥10mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Triamcinolone Acetonide is the acetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone acetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene . This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. |
Application | 1. Anti-Inflammatory Agents 2. Glucocorticoids 3. Immunosuppressive Agents |
l Packaging & Storage |
Packaging | 250mg; 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
