l General Information |
Product Name | Halcinonide |
General description | Halcinonide is a topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. |
Synonym | (11β, 16α)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione |
Purity | ≥98%(HPLC) | CAS Number | 3093-35-4 |
Formula | C24H32ClFO5 | Molecular Weight | 454.96 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ~4mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Halcinonide is a topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand receptor complex subsequently modulates gene s via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. |
Application | Anti-Inflammatory Agents |
l Packaging & Storage |
Packaging | 250mg; 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
