l General Information |
Product Name | Enoxacin |
General description | Enoxacin is an oral broad-spectrum fluoroquinolone antibacterial agent, exerts its bactericidal action via the inhibition of the essential bacterial enzyme DNA gyrase. |
Synonym | 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid; AT-2266; CI919; Pd107779; NSC 629661 |
Purity | ≥98%(HPLC) | CAS Number | 74011-58-8 |
Formula | C15H17FN4O3 | Molecular Weight | 320.32 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to light yellow brown solid |
Solubility(25℃) | DMSO | ≥25mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Enoxacin is a quinolone/fluoroquinolone antibiotic. Enoxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Enoxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. Enoxacin may be active against pathogens resistant to drugs that act by different mechanisms. |
Application | 1. Anti-Bacterial Agents 2. Topoisomerase II Inhibitors 3. Cytochrome P-450 CYP1A2 Inhibitors |
l Packaging & Storage |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
