l General Information |
Product Name | Miconazole nitrate |
General description | Miconazole Nitrate is an imidazole antifungal agent by inhibiting ergosterol biosynthesis and inducing ROS. |
Synonym | 1-(2,4-Dichloro-β-[(2,4-dichlorobenzyl)oxy]phenethyl)imidazole |
Purity | ≥98%(HPLC) | CAS Number | 22832-87-7 |
Formula | C18H14Cl4N2O · HNO3 | Molecular Weight | 479.14 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ~1mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Miconazole Nitrate is the nitrate salt form of miconazole, an antifungal synthetic derivative of imidazole and used in the treatment of candidal skin infections, Miconazole selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes. |
Application | 1. Antifungal Agents 2. Cytochrome P-450 CYP2C9 Inhibitors 3. Cytochrome P-450 CYP3A Inhibitors 4. 14-alpha Demethylase Inhibitors |
l Packaging & Storage |
Packaging | 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
