Product Name

Hydroxychloroquine Sulfate

General description

Hydroxychloroquine Sulfate is a synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, also has anti-inflammatory properties.

Synonym

7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate; Hydroxychloroquine sulphate; Ercoquin; Plaquinol; Toremonil

Purity

≥98%(HPLC)

CAS Number

747-36-4

Formula

C¹⁸H²⁶ClN³O  · H²SO⁴

Molecular Weight

433.95

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Off-white solid

Solubility(25℃)

DMSO

Insoluble

Ethanol

Insoluble

Water

≥50mg/mL

l  Biological Information

Biochem/Physiol   Actions

Hydroxychloroquine Sulfate is a synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites (Plasmodium vivax, ovale, and malariae) by concentrating in food vacuoles. It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. Hydroxychloroquine also has anti inflammatory properties and is used in the treatment of rheumatoid arthritis and lupus erythematosus.

Application

1. Enzyme Inhibitors

2. Antimalarials

3. Antirheumatic Agents

l  Packaging & Storage

Packaging

1g

Storage temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov