l General Information |
Product Name | Metronidazole |
General description | Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. |
Synonym | 2-(2-methyl-5-nitroimidazol-1-yl)ethanol; Metronidazol; Anagiardil |
Purity | ≥98%(HPLC) | CAS Number | 443-48-1 |
Formula | C6H9N3O3 | Molecular Weight | 171.156 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥30mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth. |
Application | 1. Radiation-Sensitizing Agents 2. Anti-Infective Agents 3. Antiprotozoal Agents |
l Packaging & Storage |
Packaging | 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
