l General Information |
Product Name | Exemestane |
General description | Exemestane, a synthetic androgen analogue, is an Aromatase Inhibitor. |
Synonym | 6-Methyleneandrosta-1,4-diene-3,17-dione; Aromasin; Exemestano; Exemestanum |
Purity | ≥98%(HPLC) | CAS Number | 107868-30-4 |
Formula | C20H24O2 | Molecular Weight | 296.40 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Light brown yellow solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥10mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Exemestane is a synthetic androgen analogue. Exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. |
Application | 1. Antineoplastic Agents 2. Aromatase Inhibitors |
l Packaging & Storage |
Packaging | 250mg; 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
