l General Information |
Product Name | CaMostat Mesylate |
General description | CaMostat Mesylate is a trypsin-like protease inhibitor. |
Synonym | 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic acid 2-(dimethylamino)-2-oxoethyl ester methanesulfonate; Camostat Methanesulfonate; FOY 305; FOY-S 980; Foipan mesylate |
Purity | ≥98%(HPLC) | CAS Number | 59721-29-8 |
Formula | C20H22N4O5·CH3SO3H | Molecular Weight | 494.52 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | ~10mg/mL |
l Biological Information |
Biochem/Physiol Actions | Camostat is a synthetic, orally bioavailble serine protease inhibitor. Camostat mesylate inhibits the production of TNF-α and monocyte chemoattractant protein-1 (MCP 1) by monocytes. It also inhibits the activity of pancreatic stellate cells. Camostat mesylate regulates the cytokine and inflammation and is effective in the treatment of dibutyltin dichloride-induced rat pancreatic fibrosis. |
Application | 1. Trypsin Inhibitors 2. Protease Inhibitors |
l Packaging & Storage |
Packaging | 25mg; 100mg |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
