l General Information |
Product Name | Voglibose |
General description | Voglibose is a valiolamine derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. |
Synonym | (1S,2S,3R,4S,5S)-5-(1,3-dihydroxypropan-2-ylamino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol; Glustat; Basen; AO-128; Vocarb |
Purity | ≥98%(HPLC) | CAS Number | 83480-29-9 |
Formula | C10H21NO7 | Molecular Weight | 267.278 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | ≥50mg/mL |
l Biological Information |
Biochem/Physiol Actions | Voglibose is a valiolamine derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Voglibose binds to and inhibits alpha-glucosidase, an enteric enzyme found in the brush border of the small intestines that hydrolyzes oligosaccharides and disaccharides into glucose and other monosaccharides. This prevents the breakdown of larger carbohydrates into glucose and decreases the rise in postprandial blood glucose levels. |
Application | 1. Glycoside Hydrolase Inhibitors 2. Hypoglycemic Agents |
l Packaging & Storage |
Packaging | 50mg; 250mg; |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
