l General Information |
Product Name | Furosemide |
General description | Furosemide, a sulfamoylanthranilic acid derivative, is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, widely used to treat hypertension and edema. |
Synonym | 5-(Aminosulfonyl)-4-chloro-2-([2-furanylmethyl]amino)benzoic acid; Frusemide; Furosemid; Furanthril |
Purity | ≥98%(HPLC) | CAS Number | 54-31-9 |
Formula | C12H11ClN2O5S | Molecular Weight | 330.74 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Furosemide, a sulfonamide-type loop diuretic structurally related to bumetanide, is used to manage hypertension and edema associated with congestive heart failure, cirrhosis, and renal disease, including the nephrotic syndrome. Furosemide is a sulfamoylanthranilic acid derivative, also known as frusemide, and potent loop diuretic. Furosemide is widely used to treat hypertension and edema. This agent is highly bound to albumin and is largely excreted unchanged in the urine. |
Application | 1. Diuretics 2. Sodium Potassium Chloride Symporter Inhibitors |
l Packaging & Storage |
Packaging | 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
