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Furazolidone

Product #: TL0326
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Details

l  General Information

Product Name

Furazolidone

General description

Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone acts by gradual inhibition of monoamine oxidase.

Synonym

3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one; Furoxone; Nitrofurazolidone; Furazolidine; Furazolidon

Purity

≥98%(HPLC)

CAS Number

67-45-8

Formula

C8H7N3O5

Molecular Weight

225.16

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Yellow solid

Solubility(25℃)

DMSO

≥40mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.

Furazolidone is a nitrofuran antimicrobial agent used in the treatment of diarrhea or enteritis caused by bacteria or protozoan infections. Furazolidone is also active in treating typhoid fever, cholera and salmonella infections.

Application

1. Anti-Infective Agents, Local

2. Anti-Infective Agents, Urinary

3. Antitrichomonal Agents

4. Monoamine Oxidase Inhibitors

l  Packaging & Storage

Packaging

1g

Storage temp.

0-5

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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