l General Information |
Product Name | Anacetrapib |
General description | Anacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor with hypocholesterolemic properties. |
Synonym | (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5 (trifluoromethyl)phenyl]methyl]-4-methyl-1,3-oxazolidin-2-one; MK0859 |
Purity | ≥98%(HPLC) | CAS Number | 875446-37-0 |
Formula | C30H25F10NO3 | Molecular Weight | 637.518 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥50mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Anacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor with hypocholesterolemic properties. Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum LDL cholesterol levels. This agent has not yet been shown to reduce deaths associated with hypercholesterolemia. |
Application | Anticholesteremic Agents |
l Packaging & Storage |
Packaging | 10mg; 50mg; 250mg |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
