l General Information |
Product Name | Cephradine |
General description | Cephradine is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. |
Synonym | (6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefradine; Cephradin |
Purity | ≥98%(HPLC) | CAS Number | 38821-53-3 |
Formula | C16H19N3O4S | Molecular Weight | 349.405 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Pale yellow solid |
Solubility(25℃) | DMSO | Insoluble |
Ethanol | Insoluble |
Water | ~10mg/mL |
l Biological Information |
Biochem/Physiol Actions | Cephradine Anhydrous is the anhydrous form of cephradine, a semisynthetic, broad-spectrum, first generation cephalosporin with antibacterial activity. Cephradine binds to and inactivates penicillin binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-age of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. |
Application | Anti-Bacterial Agents |
l Packaging & Storage |
Packaging | 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
