l General Information |
Product Name | Ibuprofen |
General description | Ibuprofen, a propionic acid derivate, is an anti-inflammatory inhibitor targeting COX-1 and COX-2, with anti-inflammatory, analgesic, and antipyretic effects. |
Synonym | 2-[4-(2-methylpropyl)phenyl]propanoic acid; Motrin; Brufen; Advil |
Purity | ≥99%(HPLC) | CAS Number | 15687-27-1 |
Formula | C13H18O2 | Molecular Weight | 206.285 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ≥35mg/mL |
Ethanol | ≥35mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
Application | 1. Analgesics, Non-Narcotic 2. Cyclooxygenase Inhibitors 3. Anti-Inflammatory Agents, Non-Steroidal |
l Packaging & Storage |
Packaging | 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
