Product Name

Bupivacaine hydrochloride

General description

Bupivacaine hydrochloride, a sodium channel blocker, is a widely used local anesthetic agent.

Synonym

1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride hydrate; Bupivacaine hydrochloride monohydrate

Purity

≥99%(HPLC)

CAS Number

14252-80-3

Formula

C¹⁸H²⁸N²O  • HCl • H²O

Molecular Weight

342.90

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Off-white solid

Solubility(25℃)

DMSO

≥30mg/mL

Ethanol

≥30mg/mL

Water

≥30mg/mL

l  Biological Information

Biochem/Physiol   Actions

Bupivacaine Hydrochloride is a long-acting, amide-type local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the   voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.

Application

Anesthetics, Local

l  Packaging & Storage

Packaging

1g

Storage temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov