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Cepharanthine

Product #: TL0221
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Details

l  General Information

Product Name

Cepharanthine

General description

Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.

Synonym

6′,12′-Dimethoxy-2,2′-dimethyl-6,7-(methylenebis(oxy))oxyacanthan; Cepharanthin; (+)-Cepharanthine; O-Methylcepharanoline; Cepharantin; CEP; NSC 623442

Purity

≥98%(HPLC)

CAS Number

481-49-2

Formula

C37H38N2O6

Molecular Weight

606.71

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Pale yellow or yellow solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production.

Application

1. Antineoplastic Agents, Phytogenic

2. Radiation-Protective Agents

3. Anti-Inflammatory Agents, Non-Steroidal

l  Packaging & Storage

Packaging

25mg; 100mg

Storage temp.

-20

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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