l General Information |
Product Name | Cepharanthine |
General description | Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production. |
Synonym | 6′,12′-Dimethoxy-2,2′-dimethyl-6,7-(methylenebis(oxy))oxyacanthan; Cepharanthin; (+)-Cepharanthine; O-Methylcepharanoline; Cepharantin; CEP; NSC 623442 |
Purity | ≥98%(HPLC) | CAS Number | 481-49-2 |
Formula | C37H38N2O6 | Molecular Weight | 606.71 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Pale yellow or yellow solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production. |
Application | 1. Antineoplastic Agents, Phytogenic 2. Radiation-Protective Agents 3. Anti-Inflammatory Agents, Non-Steroidal |
l Packaging & Storage |
Packaging | 25mg; 100mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |