l General Information |
Product Name | Baicalein |
General description | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor. |
Synonym | 5,6,7-trihydroxy-2-phenylchromen-4-one; Noroxylin |
Purity | ≥98%(HPLC) | CAS Number | 491-67-8 |
Formula | C15H10O5 | Molecular Weight | 270.24 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Yellow-green solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | Insoluble |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | The flavonoid component of Nepalese and Sino-Japanese crude drugs. Baicalein, a major flavone of Scutellariae baicalensis, inhibits the 12-lipoxygenase (12-LOX) pathway of arachidonic acid metabolism, which inhibits cancer cell proliferation and induces apoptosis. |
Application | 1. Enzyme Inhibitors 2. Antioxidants 3. Prostaglandin Antagonists 4. Baicalein was used in a study to investigate the in vitro quantitative inhibition of lipoxygenase. |
l Packaging & Storage |
Packaging | 500mg |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
