Product Name

10-Hydroxycamptothecin

General description

10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor with potent anti-tumor activity.

Synonym

(19S)-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,11.0^4,9.0^15,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione; (S)-10-Hydroxycamptothecin

Purity

≥98%(HPLC)

CAS Number

19685-09-7

Formula

C²⁰H¹⁶N²O⁵

Molecular Weight

364.357

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

Yellow solid

Solubility(25℃)

DMSO

~6mg/mL

Ethanol

Insoluble

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor with potent anti-tumor activity.

Application

Antineoplastic Agents, Phytogenic

l  Packaging & Storage

Packaging

50mg; 250mg

Storage temp.

-20℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov