l General Information |
Product Name | Quercetin |
General description | Quercetin is a polyphenolic flavonoid with potential chemopreventive activity. |
Synonym | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one; Sophoretin; Xanthaurine; Meletin; Quercetol |
Purity | ≥98%(HPLC) | CAS Number | 117-39-5 |
Formula | C15H10O7 | Molecular Weight | 302.238 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Yellow solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ~10mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Quercetin is a polyphenolic flavonoid with potential chemopreventive activity. Quercetin, ubiquitous in plant food sources and a major bioflavonoid in the human diet, may produce antiproliferative effects resulting from the modulation of either EGFR or estrogen-receptor mediated signal transduction pathways. Although the mechanism of action of action is not fully known, the following effects have been described with this agent in vitro: decreased of mutant p53 protein and p21-ras oncogene, induction of cell cycle arrest at the G1 phase and inhibition of heat shock protein synthesis. This compound also demonstrates synergy and reversal of the multidrug resistance phenotype, when combined with chemotherapeutic drugs, in vitro. Quercetin also produces anti inflammatory and anti-allergy effects mediated through the inhibition of the lipoxygenase and cyclooxygenase pathways, thereby preventing the production of pro-inflammatory mediators. |
Application | Antioxidants |
l Packaging & Storage |
Packaging | 250mg; 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
