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Matrine

Product #: TL0190
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Details

l  General Information

Product Name

Matrine

General description

Matrine is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.

Synonym

Matridin-15-one, Sophocarpidine; (+)-Matrine; Matridin-15-one; Matrene

Purity

≥98%(HPLC)

CAS Number

519-02-8

Formula

C15H24N2O

Molecular Weight

248.37

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Off-white solid

Solubility(25)

DMSO

≥40mg/mL

Ethanol

≥40mg/mL

Water

~8mg/mL

l  Biological Information

Biochem/Physiol   Actions

Matrine is an alkaloid that is one of the major components in the root of the saphoro plant. Matrine has been studied for possible antiviral efficacy against hepatitis B and C, as well as impact against some skin diseases and forms of cancer.

Application

Matrine may be used to study its ability to inhibit tumor cell invasiveness and metastisis as well as cell proliferation. Matrine is also used to study its mechanism of cell apoptosis. Matrine may be used to study its mechanism of autophagy inhibition.

l  Packaging & Storage

Packaging

50mg; 250mg

Storage temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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