l General Information |
Product Name | 6-Hydroxynicotinic acid |
General description | 6-hydroxynicotinic acid is exploited in the use of NMR spectroscopy or gas chromatography-mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. |
Purity | ≥98%(HPLC) | CAS Number | 5006-66-6 |
Formula | C6H5NO3 | Molecular Weight | 139.11 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to light brown solid |
Solubility(25℃) | DMSO | ≥10mg/mL |
l Biological Information |
Biochem/Physiol Actions | 6-hydroxynicotinic acid (6-OHNA) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. Among the common bacteria causing urinary infection, only P. aeruginosa produces 6 hydroxynicotinic acid from nicotinic acid. Pseudomonas aeruginosa infection has been reported to be the third leading cause of urinary infection, accounting for 11% of such infections, the first and second being Escherichia coli and Klebsiella pneumonia, respectively. Analyses of the NMR spectra of the bacterial media with variable cell count of P. aeruginosa, shows that the intensity of the signals of the 6-hydroxynicotinic acid increases with increasing number of bacterial cells. |
Application | 6-Hydroxypyridine-3-carboxylic acid (6-Hydroxynicotinic acid) was used in the synthesis of molecularly imprinted polymer (MIP). |
l Packaging & Storage |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
