l General Information |
Product Name | Isoniazid |
General description | Isoniazid is a synthetic derivative of nicotinic acid with anti-mycobacterial properties. |
Synonym | pyridine-4-carbohydrazide |
Purity | ≥99%(HPLC) | CAS Number | 54-85-3 |
Formula | C6H7N3O | Molecular Weight | 137.142 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | A white or almost white solid |
Solubility(25℃) | DMSO | ≥20mg/mL |
Ethanol | ≥20mg/mL |
Water | ≥20mg/mL |
l Biological Information |
Biochem/Physiol Actions | Isoniazid is a synthetic derivative of nicotinic acid with anti-mycobacterial properties. Although its mechanism of action is still unclear, isoniazid appears to block the synthesis of mycolic acids, major components of the mycobacterial cell wall. This agent is only active against actively growing mycobacteria because, as a pro-drug, it requires activation in susceptible mycobacterial species. Isoniazid also interferes with mycobacterial metabolism of vitamin B6. Resistance occurs due to decreased bacterial wall penetration. |
Application | 1. Antitubercular Agents 2. Fatty Acid Synthesis Inhibitors |
l Packaging & Storage |
Packaging | 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
