l General Information |
Product Name | Fumagillin |
General description | Fumagillin is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2). |
Synonym | (2E,4E,6E,8E)-10-[[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid; Fumagilline; Fumagillinum; Fumagilina; Fugillin; Fumidil |
Purity | ≥96%(HPLC) | CAS Number | 23110-15-8 |
Formula | C26H34O7 | Molecular Weight | 458.551 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Pale yellow or Brownish yellow solid |
Solubility(25℃) | DMSO | ≥50mg/mL |
Ethanol | ≥25mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | Methionine aminopeptidase-2 (MetAP-2) inhibitor; inhibits endothelial cell proliferation and angiogenesis. |
Application | 1. Angiogenesis Inhibitors 2. Anti-Bacterial Agents 3. Antiprotozoal Agents |
l Packaging & Storage |
Packaging | 5mg; 25mg |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
