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Home > Products > Small molecule > Neuronal Signaling > Cisatracurium besylate

Cisatracurium besylate

Product #: TL0167
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l  General Information

Product Name

Cisatracurium besylate

General description

Cisatracurium besylate is a non-depolarizing skeletal muscle relaxant of the benzylisoquinolinium class, antagonizing the action of acetylcholine by inhibiting neuromuscular transmission.

Synonym

benzenesulfonate;5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl3-[(1R,2R)-1-[(3,4 dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate; Nimbex;

Purity

≥98%(HPLC)

CAS Number

96946-42-8

Formula

C53H72N2O12·2C6H5O3S

Molecular Weight

1243.48

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or yellowish-white solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

≥50mg/mL

Water

≥40mg/mL

l  Biological Information

Biochem/Physiol   Actions

Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration. Cisatracurium Besylate acts on cholinergic receptors, blocking neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors such as neostigmine. The neuromuscular block produced by cisatracurium besylate is readily antagonized by anticholinesterase agents once recovery has started. As with other nondepolarizing neuromuscular blocking agents, the more profound the neuromuscular block at the time of reversal, the longer the time required for recovery of neuromuscular function. Compared to other neuromuscular blocking agents, it is intermediate in its onset and duration of action.

Application

Neuromuscular Blocking Agents

l  Packaging & Storage

Packaging

50mg; 250mg; 1g

Storage temp.

-20

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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