l General Information |
Product Name | HO-3867 |
General description | HO-3867, an analog of curcumin, is a selective STAT3 inhibitor. |
Synonym | (3E,5E)-3,5-bis[(4-fluorophenyl)methylidene]-1-[(1-hydroxy-2,2,5,5-tetramethylpyrrol-3-yl)methyl]piperidin-4-one; HO3867 |
Purity | ≥98%(HPLC) | CAS Number | 1172133-28-6 |
Formula | C28H29F2N2O2 | Molecular Weight | 463.54 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to pale yellow solid |
Solubility(25℃) | DMSO | ~10mg/mL |
Ethanol | ~5mg/mL |
Water | Insoluble |
l Biological Information |
Biochem/Physiol Actions | HO-3867, an analog of curcumin, is a selective STAT3 inhibitor that inhibits its phosphorylation, transcription, and DNA binding without affecting the of other active STATs |
l Packaging & Storage |
Packaging | 5mg; 25mg; 100mg |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |