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HO-3867

Product #: TL0139
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Details

l  General Information

Product Name

HO-3867

General description

HO-3867, an analog of curcumin, is a selective STAT3 inhibitor.

Synonym

(3E,5E)-3,5-bis[(4-fluorophenyl)methylidene]-1-[(1-hydroxy-2,2,5,5-tetramethylpyrrol-3-yl)methyl]piperidin-4-one; HO3867

Purity

≥98%(HPLC)

CAS Number

1172133-28-6

Formula

C28H29F2N2O2

Molecular Weight

463.54

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to pale yellow solid

Solubility(25℃)

DMSO

~10mg/mL

Ethanol

~5mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

HO-3867, an analog of curcumin, is a selective STAT3 inhibitor that inhibits its phosphorylation, transcription, and DNA binding without affecting the of other active STATs

l  Packaging & Storage

Packaging

5mg; 25mg; 100mg

Storage temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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