Product Name

Oxaliplatin

General description

Oxaliplatin is an anti-tumor agent with activity against colorectal cancer; cytotoxicity follows the formation of adducts with DNA.

Synonym

[(1R,2R)-2-azanidylcyclohexyl]azanide;oxalic acid; platinum(2+); DSSTox_CID_16760

Purity

≥99%(HPLC)

CAS Number

61825-94-3

Formula

C⁸H¹⁴N²O⁴Pt

Molecular Weight

397.294

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Off-white solid

Solubility(25℃)

DMF

≥10mg/mL

Ethanol

Very slightly soluble

Water

Slightly soluble

l  Biological Information

Biochem/Physiol   Actions

Oxaliplatin is a Platinum-based Drug. The chemical classification of oxaliplatin is Platinum containing Compounds. Oxaliplatin is an anti-tumor agent with activity against colorectal cancer; cytotoxicity follows the formation of adducts with DNA.

Oxaliplatin inhibits DNA synthesis by conforming DNA adducts in RT4, TCCSUP, A2780, HT-29, U 373MG, U-87MG, SK-MEL-2, and HT-144 cells

l  Packaging & Storage

Packaging

25mg; 100mg

Storage temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov