l General Information |
Product Name | AEBSF HCl |
General description | AEBSF HCl is a broad spectrum, irreversible serine protease inhibitor. |
Synonym | 4-(2-aminoethyl)benzenesulfonyl fluoride; hydrochloride; AEBSF Hydrochloride |
Purity | ≥98%(HPLC) | CAS Number | 30827-99-7 |
Formula | C8H11ClFNO2S | Molecular Weight | 239.689 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White solid |
Solubility(25℃) | DMSO | ≥40mg/mL |
Ethanol | ≥40mg/mL |
Water | ≥15mg/mL |
l Biological Information |
Biochem/Physiol Actions | Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. AEBSF has been used in cell culture in concentrations of up to 0.25 mM. Recommended concentrations for use are 0.1-1 mM. |
Application | 1. Serine Proteinase Inhibitors 2. Trypsin Inhibitors |
l Packaging & Storage |
Packaging | 50mg; 250mg; 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
