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AZD3839 fuMarate

Product #: TL0094
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Details

l  General Information

Product Name

AZD3839 hemifuMarate

General description

AZD3839 hemifuMarate is a potent and selective BACE1 inhibitor.

Synonym

(3S)-3-[2-(difluoromethyl)pyridin-4-yl]-7-fluoro-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine; hemifuMarate; AZD-3839 fuMarate;

Purity

≥98%(HPLC)

CAS Number

1227163-84-9(Free Base)

Formula

C26H18F3N5O2

Molecular Weight

489.4

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to pale yellow or light brown yellow solid

Solubility(25℃)

DMSO

≥10mg/mL

l  Biological Information

Biochem/Physiol   Actions

AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. It has been used in trials studying the basic science of Safety, Tolerability, Alzheimer's Disease, and Blood Concentration.

l  Packaging & Storage

Packaging

5mg; 25mg; 100mg

Storage temp.

0-5

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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