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Lansoprazole

Product #: TL0078
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Details

l  General Information

Product Name

Lansoprazole

General description

Lansoprazole is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity.

Synonym

2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfinyl]-1H-benzimidazole; Prevacid; Bamalite; Monolitum; Limpidex;

Purity

≥98%(HPLC)

CAS Number

103577-45-3

Formula

C16H14F3N3O2S

Molecular Weight

369.36

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or brownish solid

Solubility(25℃)

DMSO

≥50mg/mL

Ethanol

≥10mg/mL

Water

Insoluble

l  Biological Information

Biochem/Physiol   Actions

Lansoprazole is an acid proton-pump inhibitor similar to omeprazole. Lansoprozole is active against Helicobacter pylori. The plasma elimination half-life of lansoprazole does not reflect its duration of suppression of gastric acid secretion. Thus, the plasma elimination half-life is less than two hours, while the acid inhibitory effect lasts more than 24 hours.

Application

1.      Proton Pump Inhibitors

Compounds that inhibit H(+)-K(+)-exchanging ATPase. They are used as anti-ulcer agents and sometimes in place of hisstamine H2 antagonists for gastroesophageal reflux.

2.      Anti-Ulcer Agents

Various agents with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. This has included antibiotics to treat helicobacter infections; Histamine H2 antagonists to reduce gastric acid secretion; and antacids for symptomatic relief.

l  Packaging & Storage

Packaging

250mg; 1g

Storage temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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