l General Information |
Product Name | Lomefloxacin HCl |
General description | Lomefloxacin HCl is the hydrochloride salt of Lomefloxacin. Lomefloxacin is a synthetic broad-spectrum fluoroquinolone with antibacterial activity. |
Synonym | 1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid |
Purity | ≥98%(HPLC) | CAS Number | 98079-52-8 |
Formula | C17H19F2N3O3 · HCl | Molecular Weight | 387.81 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White or Off-white solid |
Solubility(25℃) | DMSO | ~1mg/mL |
Ethanol | insoluble |
Water | ~5mg/mL |
l Biological Information |
Biochem/Physiol Actions | Lomefloxacin is a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. |
Application | 1. Anti-Bacterial Agents Substances that inhibit the growth or reproduction of BACTERIA. 2. Topoisomerase II Inhibitors Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II. |
l Packaging & Storage |
Packaging | 50mg; 1g |
Storage temp. | 0-5℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
