Product   Name

Etomidate HCl

General   deion

Etomidate is a GABAA receptor agonist, used as a short-acting anaesthetic agent or sedative.Etomidate treatment demonstrated neuroprotective effect on the neuronal tissue against the diabetic oxidative damage.

Synonym

(R)-1-(α-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester hydrochloride; Etomidate hydrochloride.

Purity

≥98%(HPLC)

CAS   Number

53188-20-8

Formula

C¹⁴H¹⁶N²O²·HCl

Molecular   Weight

280.75

Suitability

BioReagent,   suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White or Off-white solid

l  Biological Information

Biochem/Physiol   Actions

Etomidate is a GABAA receptor agonist, used as a short-acting anaesthetic agent or sedative. Etomidate treatment demonstrated neuroprotective effect on the neuronal tissue against the diabetic oxidative damage.The possible   neuroprotective effect of etomidate against streptozotocin-induced (STZ-induced) hyperglycaemia were investigated in the rat brain and spinal cord.

Application

1.    This compound is a featured product for Neuroscience research.

2.    Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. Etomidate has been proposed as an induction anesthetic.

l  Packaging & Storage

Packaging

50mg;  250mg

Storage   temp.

0-5℃

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    https://www.ncbi.nlm.nih.gov/mesh

2.    https://ncit.nci.nih.gov