Product Name

Galactocerebrosides from bovine brain

General description

A mixture of type I (containing α-hydroxy fatty acid) and type II (containing non-hydroxy fatty acid) cerebrosides. Galactocerebroside (GalCer) is a glycosphingolipid, that consists of a single galactose residue, connected to ceramide . GalCer is present within the exofacial leaflet of the lipid b.

Synonym

Ceramide β-D-galactoside

Purity

≥97%(TLC), cerebrosides[mixture of type I (contains A-hydroxy fatty acids) and type II (contains non-hydroxy fatty acids)]

CAS  Number

85305-88-0

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Off-White Solid

l  Biological Information

Biochem/Physiol  Actions

Galactose ed to ceramide by a β-glycosidic age; the major lipid in adult brain, representing approximately 16% of total lipid; they are mainly localized to myelin and are markedly reduced in demyelinating diseases.

Galactocerebroside (GalCer) participates in the progression and maintenance of myelin. This oligodendroglial lipid is used as an immunohistochemical tool for studying oligodendrocytes.

Application

Galactocerebrosides from bovine brain has been used to find the receptor activity of surface-immobilized galactosylceramide.It has also been used in sulfatide binding assay.

l  Storage

Storage temp.

−20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov