Cytochalasin B from Drechslera dematioidea
Product #：
S1305
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Price($)
Quantity
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S1305-1MG
In-stock
140
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S1305-5MG
In-stock
581
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S1305-10MG
In-stock
840
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S1305-25MG
In-stock
1675
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S1305-50MG
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2895
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Details
l General Information |
Product Name | Cytochalasin B from Drechslera dematioidea |
General description | One of a group of fungal metabolites that interfere with a wide variety of cellular movements. |
Synonym | Phomin |
Purity | ≥98%(HPLC) | CAS Number | 14930-96-2 |
Formula | C29H37NO5 | Molecular Weight | 479.61 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White powder |
Solubility(25°C) | DMSO | ≥5mg/mL |
l Biological Information |
Biochem/Physiol
Actions | Cytochalasin B is a cell-permeable fungal toxin / mycotoxin that binds to the′barbed′ end of actin / actin filaments. This binding leads to: •
Disruption of actin filaments and of interaction of actin filaments in solution •
Inhibition of actin polymerization •
Inhibition of subunit association and dissociation Cytochalasin B is widely used in studies of glucose transporters (GLUT). Cytochalasin B is also used as an integral part of various in vitro micronucleus assay protocols. One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. |
l Storage |
Storage temp. | −20°C |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
