Product Name

Insulin chain A oxidized ammonium salt from bovine pancreas

General description

Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids.

Amino Acid Sequence

Gly-Ile-Val-Glu-Gln-Cys(SO₃H)-Cys(SO₃H)-Ala-Ser-Val-Cys(SO₃H)-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys(SO₃H)-Asn

Purity

≥80%(HPLC)

CAS Number

77282-71-4

Formula

C₉₇H₁₅₁N₂₅O₄₆S₄ · (NH₃)x

Molecular Weight

2531.64 (free acid basis)

Suitability

BioReagent,  suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

powder

l  Biological Information

Biochem/Physiol  Actions

Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids. It inhibits the breakdown of glycogen, protein, and fat. The α chain contains an intrachain disulfide bond.Human insulin is made up of 51 amino acids. It consists of two peptide chains, 21 amino acids make up A-chain and chain B contains 31 amino acids. The two chains are ed together by a disulfide bond, to form a classical insulin fold with three α helices, chain A having two and one in chain B.

Insulin regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids. It inhibits the breakdown of glycogen, protein, and fat. The α chain contains an intrachain disulfide bond.

l  Storage

Storage temp.

−20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov