Product Name

Bafilomycin B1 from Streptomyces sp.

General description

Bafilomycin B1 is a toxic macrolide antibiotic used to study cell processes such as autophagy, pH control within cells, and mechanisms of apoptosis.

Synonym

Setamycin; Bafilomycin B1

Purity

≥80%(HPLC)

CAS Number

88899-56-3

Formula

C⁴⁴H⁶⁵NO¹³

Molecular Weight

815.99

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to yellow powder or crystals

l  Biological Information

Biochem/Physiol   Actions

Bafilomycin B1 inhibits vacuolar type H₊-ATPase (V-ATPase) and is used to study cell processes such as autophagy, pH control within cells, and mechanisms of apoptosis.Bafilomycin B1′s activity results from the presence of a large macrocyclic lactone ring to which deoxy sugars may attach.

Application

Bafilomycin B1 is a toxic macrolide antibiotic used to study cell processes such as autophagy, pH control within cells, and mechanisms of apoptosis

l  Storage

Storage temp.

−20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov