Product Name

Gramicidin C from Bacillus brevis

General description

Gramicidin is a naturally occuring polypeptide antibiotic.

Purity

~90% (HPLC)

CAS  Number

9062-61-7

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to off-white Powder

l  Biological Information

Biochem/Physiol  Actions

Naturally occuring polypeptide antibiotic with Tyr at position 11; functions as a transmembrane ion channel.Gramicidin′s bactericidal activity is a result of increasing the permeability of the bacterial cell membrane. This allows inorganic monovalent cations to travel through unrestricted which thereby destroys the ion gradient between the cytoplasm and the extracellular environment.

Application

Gramicidin is a naturally occuring polypeptide antibiotic. It functions as a transmembrane ion channel and is used for studies on phospholipid b membrane fluidity measured by lateral diffusion.

l  Storage

Storage temp.

2-8°C

l  Precautions and Disclaimer

This product is for R&D use only, not  for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov