Product Name

Ubiquitin from bovine erythrocytes

General description

A 76-amino acid protein (8.6 kDa) that is bound covalently by a conjugating enzyme to proteins that are targeted for degradation by 26S proteasome.

Synonym

ATP-dependent proteolytic factor, Ub

Purity

≥98%(SDS-PAGE)

CAS  Number

79586-22-4

Molecular Weight

8560 Da by calculation (monoisotopic mass)

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Light Brown essentially salt-free lyophilized powder

l  Biological Information

Biochem/Physiol  Actions

Ubiquitin is a small regulatory protein present in eukaryote tissues. Exogenous ubiquitin can stimulate apoptosis in numerous cell lines. E7 protein of human papilloma virus-16 stimulates Retinoblastoma Protein degradation via Ubiquitin-Proteasome Pathway.

Application

Ubiquitin from bovine erythrocytes can be used for in vitro ubiquitinylation assay. The product can also be used as a marker in western blotting.

l  Storage

Storage temp.

2-8°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov