Product Name

Zymosan A from Saccharomyces cerevisiae

General description

Zymosan is prepared from yeast cell wall and consists of protein-carbohydrate complexes.

CAS Number

58856-93-2

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

off-white to light brown powder with small lumps

l  Biological Information

Biochem/Physiol  Actions

Zymosan is prepared from yeast cell wall and consists of protein-carbohydrate complexes. It is used to induce experimental sterile inflammation. In macrophages, zymosan-induced responses include the induction of proinflammatory cytokines, arachidonate mobilization, protein phosphorylation, and inositol phosphate formation. Zymosan A also raises cyclin D2 levels suggesting a role for the latter in macrophage activation besides proliferation. It potentiates acute liver damage after galactosamine injection suggesting that certain types of nonparenchymal cells other than Kupffer cells are involved in zymosan action.

l  Storage

Storage temp.

2-8°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov