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Oligomycin from Streptomyces diastatochromogenes

Product #: S1204
Image SKU-Pack Size Stock Price($) Quantity
  • S1204-5MG

    In-stock

    154

    - +

    S1204-25MG

    In-stock

    619

    - +

    S1204-100MG

    In-stock

    2079

    - +

    S1204-250MG

    In-stock

    3938

    - +

Documents

Details

l  General Information

Product Name

Oligomycin from Streptomyces diastatochromogenes

General description

Oligomycin belongs to the macrolide group of antibiotics.

Synonym

Oligomycins

Purity

≥90% total oligomycins basis (HPLC)

CAS Number

1404-19-9

Formula

C45H74O11

Molecular Weight

791.076

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to Light Yellow Powder

l  Biological Information

Biochem/Physiol  Actions

Oligomycin belongs to the macrolide group of antibiotics. It inhibits mitochondrial ATP-synthase enzyme. Oligomycin interacts with ATP synthase subunit-c in the Fo portion and impairs proton transport.

Application

Oligomycin from Streptomyces diastatochromogenes is used:

• in the inhibition of mitochondrial ATP production Leigh syndrome (LS) cells.

• in ATP-ed respiration and maximal capacity respiration assay in astrocytes.

• in measurement of oxygen consumption rate (OCR) and extracellular acidification rates in breast cancer cell lines.

l  Storage

Storage temp.

−20°C

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 

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