Concanavalin A from Canavalia ensiformis (Jack bean)
 
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         S1198
         
        
        
       
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                   S1198-25MG
 
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                   S1198-100MG
 
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                   S1198-250MG
 
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                   S1198-1G
 
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Details
 
       
              
          l  General Information  | 
Product Name  | Concanavalin A from Canavalia ensiformis (Jack bean)  | 
General description  | BioReagent, suitable for cell culture  | 
Synonym  | Con A  | 
Potency  | Type VI;≤20 μg
  per mL agglutination activity  | CAS Number  | 11028-71-0  | 
Suitability  | BioReagent, suitable for cell culture, etc.  | 
l  Physical and Chemical Information  | 
Appearance  | White to Off-White lyophilized powder  | 
Solubility(25°C)  | Water  | ~5mg/mL  | 
l  Biological Information  | 
Biochem/Physiol
  Actions  | Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6.  | 
l  Storage  | 
Storage temp.  | 0-5°C  | 
l  Precautions and Disclaimer  | 
This product is for R&D use only, not for drug, household, or other uses.  | 
l  References  | 
1.    http://www.drugbank.ca 2.    https://ncit.nci.nih.gov 3.    https://www.ncbi.nlm.nih.gov  |