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Home > Products > Small molecule > Proteases > N-Acetyl-D-sphingosine

N-Acetyl-D-sphingosine

Product #: S1161
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Details

l  General Information

Product Name

N-Acetyl-D-sphingosine

General description

Cell-permeable, biologically active  ceramide.

Synonym

(2S,3R,4E)-2-(Acetylamino)-4-octadecene-1,3-diol, N-Acetoyl-D-erythro-sphingosine, Acetyl ceramide, C2 Ceramide (d18:1/2:0), C2 ceramide

Purity

≥97.0%(TLC)

CAS Number

3102-57-6

Formula

C20H39NO3

Molecular Weight

341.53

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White Solid

Solubility(25)

DMSO

soluble

Ethanol

soluble

l  Biological Information

Biochem/Physiol   Actions

Cell-permeable, biologically active ceramide. It induces differentiation and apoptosis in cells and has been shown to activate protein phosphatases.

Application

N-Acetyl-D-sphingosine is a cell-permeable and biologically active ceramide. N-Acetyl-D sphingosine induces differentiation and apoptosis in cells. N-Acetyl-D-sphingosine produces concentration-dependent impairment of vasorelaxation in response to the endothelium-dependent agonist acetylcholine in nontransgenic mice.

l  Storage

Storage temp.

-20

l  Precautions and Disclaimer

This   product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov


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