l General Information |
Product Name | Oltipraz metabolite M2 |
General description | M2 is a metabolite of the chemopreventive agent oltipraz. |
Synonym | 7-Methyl-6,8-bis(methylthio)-pyrrolo[1,2-a]pyrazine |
Purity | ≥98.0%(HPLC) | CAS Number | 84201-40-1 |
Formula | C10H12N2S2 | Molecular Weight | 224.35 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to light brown Solid |
Solubility(25℃) | DMSO | ≥5mg/mL |
l Biological Information |
Biochem/Physiol Actions | M2 is a metabolite of the chemopreventive agent oltipraz. Oltipraz metabolite M2 has been shown to inhibit liver steatosis by inhibiting lipogenesis and enhancing mitochondrial function, including fuel oxidation. Oltipraz metabolite M2 acts as a potent inhibitor of LXRa transcriptional activity, and also AMPK activator inducing the phosphorylation of AMPK. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
