l General Information |
Product Name | BLT-1 |
General description | Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer. |
Synonym | BLT1; MIT 9952-53; 2-Hexyl-1-cyclopentanone thiosemicarbazone,33M20,Block lipid transport-1 |
Purity | ≥98.0%(HPLC) | CAS Number | 321673-30-7 |
Formula | C12H23N3S | Molecular Weight | 241.4 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to Tan Solid |
Solubility(25℃) | DMSO | ≥5mg/mL |
l Biological Information |
Biochem/Physiol Actions | Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer. The compound inhibits both cellular selective lipid uptake of HDL cholesteryl ether and efflux of cellular cholesterol to HDL. |
Application | BLT-1 may be used to study cell signaling pathways that have role in cholesterol influx and efflux. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
