l General Information |
Product Name | Sulprostone |
General description | Selective EP3 prostanoid receptor agonist. |
Synonym | CP-34089, SHB-286, ZK-57671; (5Z,11α,13E,15R)--11,15-Dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-5,13-dienoic acid methane sulfonamide |
Purity | ≥95.0%(HPLC) | CAS Number | 60325-46-4 |
Formula | C23H31NO7S | Molecular Weight | 465.56 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | Colorless to Yellow-Brown Oil |
Solubility(25℃) | DMSO | ≥10mg/mL |
l Biological Information |
Biochem/Physiol Actions | Selective EP3 prostanoid receptor agonist. Sulprostone is an analog of prostaglandin E2 (PGE2)1 and antagonizes vasopressin-induced antidiuretic responses in cells from rat renal inner medullae by a mechanism that involves activation of Rho.2 |
Application | Human chondrocytes3 and mouse adrenal chromaffin cells4 were treated with sulprostone to study the biological effects of PGE2. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
