l General Information |
Product Name | Ifetroban sodium |
General description | fetroban (BMS-180291) is a potent and selective thromboxane receptor antagonist. |
Synonym | BMS-180291 sodium, Sodium ifetroban |
Purity | ≥98.0%(HPLC) | CAS Number | 156715-37-6 |
Formula | C25H31N2O5 · Na | Molecular Weight | 462.51 |
Suitability | BioReagent, suitable for cell culture, etc. |
l Physical and Chemical Information |
Appearance | White to beige Solid |
Solubility(25℃) | Water | ≥5mg/mL |
l Biological Information |
Biochem/Physiol Actions | fetroban (BMS-180291) is a potent and selective thromboxane receptor antagonist. The IC50 for inhibition of arachadonate or U-46619-induced platelet aggregation in human plasma is 7 nM and 30 nM, respectively. Ifetroban inhibits platelet aggregation in African green monkey 100% at 3 mpk, and blocks the contractile effects of U-46619 and Ang II in rabbit renal afferent arterioles. |
l Storage |
Storage temp. | -20℃ |
l Precautions and Disclaimer |
This product is for R&D use only, not for drug, household, or other uses. |
l References |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |