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Ifetroban sodium

Product #: S1002
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l  General Information

Product Name

Ifetroban sodium

General description

fetroban (BMS-180291) is a potent and selective thromboxane receptor antagonist.

Synonym

BMS-180291 sodium, Sodium ifetroban

Purity

≥98.0%(HPLC)

CAS Number

156715-37-6

Formula

C25H31N2O5 · Na

Molecular Weight

462.51

Suitability

BioReagent, suitable for cell culture, etc.

l  Physical and Chemical Information

Appearance

White to beige Solid

Solubility(25)

Water

≥5mg/mL

l  Biological Information

Biochem/Physiol   Actions

fetroban (BMS-180291) is a potent and selective thromboxane receptor antagonist. The IC50 for inhibition of arachadonate or U-46619-induced platelet aggregation in human plasma is 7 nM and 30 nM, respectively. Ifetroban inhibits platelet aggregation in African green monkey 100% at 3 mpk, and blocks the contractile effects of U-46619 and Ang II in rabbit renal afferent arterioles.

l  Storage

Storage temp.

-20

l  Precautions and Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

l  References

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov

 


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